Frontier Pharma: Parkinson’s Disease – Identifying And Commercializing First-In-Class Innovation By Radiant Insights, Inc

Summary

Large Degree of Innovation in Parkinson’s Disease Pipeline

The Parkinson’s disease (PD) pipeline currently has 302 products in active development across all stages, but a stark contrast between the mechanisms of action employed in the current market and the pipeline is evident. Where the market relies on symptomatic treatments that target neuromodulatory receptors, the pipeline shows a diverse range of neuroprotective therapies targeting dysfunctional disease processes. This diversity is partially due to the presence of 90 first-in-class products, which accounts for 37% of the overall pipeline therapies that disclosed their target.

Browse Full Report With TOC @ http://www.radiantinsights.com/research/frontier-pharma-parkinson-s-disease-identifying-and-commercializing-first-in-class-innovation

In an industry, market and development landscape that favors first-in-class over non-first-in-class development in many ways, such as through faster approval or greater revenue, this finding has strategic implications for a wide array of market participants, both large and small. Despite their historically high attrition rate, first-in-class therapies that reach the market have the potential to transform and improve the PD treatment landscape.

Alignment of First-in-Class Molecular Target with Disease Processes and Genetics

PD is a complex and multifaceted disease with a complex interplay between different pathological processes. Enormous research efforts and significant technological advances have furthered knowledge of the neuroanatomy of the basal ganglia and of the fundamental processes underlying neurodegeneration, helped by the ongoing identification of susceptibility genes and causative genes in familial PD.

Although the exact mechanisms that initiate onset remain unclear, these insights have been translated into the pool of novel therapeutic targets, which may potentially become disease-modifying therapies by aligning to the disease processes and some genetic determinants of PD.

GBI Research’s proprietary analysis showed substantial variation in how well the functional roles of PD first-in-class targets align to the pathophysiology of PD. Further in-depth analysis identified the most promising first-in-class targets based on various scientific and clinical parameters. Examining scientific and clinical data of promising first-in-class targets showed that first-in-class status is not, in its own right, enough for a successful product; however, the first-in-class products substantiated by scientific and clinical evidence will be exciting future prospects with the potential to transform the PD market.

First-in-Class Products in Licensing and Co-development Deals

Strategic consolidation is relatively uncommon in the PD market. Concerning first-in-class specifically, only nine first-in-class products that are currently in development have been involved in licensing or co-development deals since 2006. Despite the low sample size, it is clear that the first-in-class PD products offer an attractive investment prospect as they command much higher deal values and, on average, deals occur earlier in development compared to non-first-in-class counterparts.

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Both trends were substantiated by industry-wide data that showed that, particularly in Phase I, first-in-class products would attract larger mean and median total deal values. The data highlight that the first-in-class deals landscape is different and indicates a greater chance of becoming much more lucrative than the deals landscape for addition-to-class or advance-in-class therapies.

A total of 81 first-in-class products that are currently in development have not yet been entered into a licensing or co-development deal. Under a growing unmet need for disease-modifying therapies and increasing understanding of disease processes allowed by technological advances, there are numerous opportunities for strategic alliances to bolster a first-in-class portfolio or fund clinical development. Some of these first-in-class products are supported by promising scientific and clinical data, making them attractive prospects as both therapeutics and investment opportunities.

Scope

The report analyzes innovation in PD in the context of the overall pipeline and current market landscape. It also analyzes the deals landscape surrounding first-in-class products and pinpoints in-licensing opportunities.The report includes –

– A brief introduction to PD, including symptoms, pathophysiology, and an overview of pharmacotherapy and treatment algorithms

– Coverage of the changing molecular target landscape and particular points of innovation in the pipeline

– A comprehensive review of the pipeline for first-in-class therapies, analyzed by stage of development, molecule type and molecular target

– Identification and assessment of first-in-class molecular targets with a particular focus on early-stage programs of which clinical utility has yet to be evaluated, as well as literature reviews of novel molecular targets

– Industry-wide analysis of first-in-class deals compared to non-first-in-class deals

– An assessment of the licensing and co-development deal landscape for PD therapies and benchmarking of deals comparing first-in-class and non-first-in-class-products

Browse Full Report With TOC @ http://www.radiantinsights.com/research/frontier-pharma-parkinson-s-disease-identifying-and-commercializing-first-in-class-innovation

Reasons to buy

The report will enable business development and enable marketing executives to strategize their product launches by allowing them to –

– Understand the focal shifts in molecular targets in the PD pipeline

– Understand the distribution of pipeline programs by phase of development, molecule type and molecular target

– Access a scientific and clinical analysis of first-in-class developmental programs for PD, benchmarked against non-first-in-class targets

– Assess the valuations of licensed and co-developed PD treatments

– Access a list of the first-in-class therapies potentially open to deal-making opportunities

 

About Us

Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. We assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. We have a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, our experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.

For more information visit: Radiant Insights

Contact:

Michelle Thoras

Corporate Sales Specialist, USA

Radiant Insights, Inc

Phone: 1-415-349-0058

Toll Free: 1-888-202-9519

Email: sales@radiantinsights.com

Blog URL: http://radiantinsights.weebly.com/

Trimethylene Sulfite Market Share, Growth, Research Report 2015: Radiant Insights, Inc

was a professional and depth research report on Global Trimethylene Sulfite industry that you would know the world’s major regional market conditions of Trimethylene Sulfite industry, the main region including North American, Europe and Asia etc, and the main country including United States ,Germany ,Japan and China etc.

The report firstly introduced Trimethylene Sulfite basic information including Trimethylene Sulfite definition, classification, application and industry chain overview; Trimethylene Sulfite industry policy and plan, Trimethylene Sulfite product specification, manufacturing process, cost structure etc. Then we deeply analyzed the world’s main region market conditions that including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc.

View Full Report with TOC @ http://www.radiantinsights.com/research/trimethylene-sulfite-market-research-report-2015

In the end, the report introduced Trimethylene Sulfite new project SWOT analysis, investment feasibility analysis, and investment return analysis and Global Twin-screw Extruder industry.

In a word, it was a depth research report on Global Trimethylene Sulfite industry. And thanks to the support and assistance from Trimethylene Sulfite industry chain related technical experts and marketing experts during Research Team survey and interviews.

The report including six parts, the first part mainly introduced the product basic information; the second part mainly analyzed the Asia Trimethylene Sulfite industry; the third part mainly analyzed the North American Trimethylene Sulfite industry; the fourth part mainly analyzed the Europe Trimethylene Sulfite industry; the fifth part mainly analyzed the market entry and investment feasibility; the sixth part was the report conclusion chapter.

About Us

Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. We assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. We have a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, our experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.

For more information visit: Radiant Insights

Contact:

Michelle Thoras

Corporate Sales Specialist, USA

Radiant Insights, Inc

Phone: 1-415-349-0058

Toll Free: 1-888-202-9519

Email: sales@radiantinsights.com

Blog URL: http://radiantinsights.weebly.com/

Trimethylolpropane (TMP) Market Size, Analysis, Research Report 2015: Radiant Insights, Inc

was a professional and depth research report on Global Trimethylolpropane (TMP) industry that you would know the world’s major regional market conditions of Trimethylolpropane (TMP) industry, the main region including North American, Europe and Asia etc, and the main country including United States ,Germany ,Japan and China etc.

The report firstly introduced Trimethylolpropane (TMP) basic information including Trimethylolpropane (TMP) definition, classification, application and industry chain overview; Trimethylolpropane (TMP) industry policy and plan, Trimethylolpropane (TMP) product specification, manufacturing process, cost structure etc. Then we deeply analyzed the world’s main region market conditions that including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate etc.

Browse Full Report With TOC @ http://www.radiantinsights.com/research/trimethylolpropane-tmp-market-research-report-2015

In the end, the report introduced Trimethylolpropane (TMP) new project SWOT analysis, investment feasibility analysis, and investment return analysis and Global Twin-screw Extruder industry.

In a word, it was a depth research report on Global Trimethylolpropane (TMP) industry. And thanks to the support and assistance from Trimethylolpropane (TMP) industry chain related technical experts and marketing experts during Research Team survey and interviews.

The report including six parts, the first part mainly introduced the product basic information; the second part mainly analyzed the Asia Trimethylolpropane (TMP) industry; the third part mainly analyzed the North American Trimethylolpropane (TMP) industry; the fourth part mainly analyzed the Europe Trimethylolpropane (TMP) industry; the fifth part mainly analyzed the market entry and investment feasibility; the sixth part was the report conclusion chapter.

About Us

Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. We assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. We have a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, our experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.

For more information visit: Radiant Insights

Contact:

Michelle Thoras

Corporate Sales Specialist, USA

Radiant Insights, Inc

Phone: 1-415-349-0058

Toll Free: 1-888-202-9519

Email: sales@radiantinsights.com

Blog URL: http://radiantinsights.weebly.com/

Global Electrocardiograph Market Growth, Analysis, Forecasts, Market Research Report 2015: Radiant Insights, Inc

2015 Market Research Report on Global Electrocardiograph Industry>is a professional and depth research report on Global Electrocardiograph industry

For overview analysis, the report introduces Electrocardiograph basic information including definition, classification, application, industry chain structure, industry overview, policy analysis, and news analysis, etc

For international and China market analysis, the report analyzes Electrocardiograph markets in China and other countries or regions (such as US, Europe, Japan, etc) by presenting research on global products of different types and applications developments and trends of market, technology, and competitive landscape, and leading suppliers and countries’2009-2014 capacity, production, cost, price, profit, production value, and gross margin.

View Full Report with TOC @ http://www.radiantinsights.com/research/global-electrocardiograph-industry-2015-market-research-report

For leading suppliers, related information is listed as products, customers, application, capacity, market position, and company contact information, etc. 2015-2020 forecast on capacity, production, cost, price, profit, production value, and gross margin for these markets are also included.

For technical data and manufacturing plants analysis, the report analyzes Electrocardiograph leading suppliers on capacity, commercial production date, manufacturing plants distribution, R&D Status, technology sources, and raw materials sources.

This report also presents product specification, manufacturing process, and product cost structure etc. Production is separated by regions, technology and applications. Analysis also covers upstream raw materials, equipment, downstream client survey, marketing channels, industry development trend and proposals.

In the end, the export includes Electrocardiograph new project SWOT analysis, investment feasibility analysis, investment return analysis, and development analysis. In conclusion, it is a deep research report on Global Electrocardiograph industry.

Here, we express our thanks for the support and assistance from Electrocardiograph industry chain related technical experts and marketing engineers during Research Team’s survey and interviews.

About Us

Radiant Insights is a platform for companies looking to meet their market research and business intelligence requirements. We assist and facilitate organizations and individuals procure market research reports, helping them in the decision making process. We have a comprehensive collection of reports, covering over 40 key industries and a host of micro markets. In addition to over extensive database of reports, our experienced research coordinators also offer a host of ancillary services such as, research partnerships/ tie-ups and customized research solutions.

For more information visit: Radiant Insights

Contact:

Michelle Thoras

Corporate Sales Specialist, USA

Radiant Insights, Inc

Phone: 1-415-349-0058

Toll Free: 1-888-202-9519

Email: sales@radiantinsights.com

Blog URL: http://radiantinsights.weebly.com/